Caspase 3 antibody

Catalog No. ABIN198462

The Rabbit Polyclonal anti-Caspase 3 antibody (ABIN198462) specifically detects Caspase 3 in WB, IHC and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Caspase 3 antibody (ABIN198462)

Target: Caspase 3 (CASP3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caspase 3 Antibody

Specificity: Recognizes human, mouse and rat active caspase-3 (p20 subunit). Does not cross-react with procaspase-3 (~32kD).

Purification: Affinity purified

Immunogen: Synthetic peptide around the cleavage site of human caspase-3.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P, WB

Usage: Recommended Dilutions:Immunohistochemistry (Paraffin): 1:10-1:20Western Blot: 1:50-1:500Optimal dilutions to be determined by the researcher.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.5 % BSA, 0.01 % Thimerosal, 30 % glycerol.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Caspase 3

Target: Caspase 3 (CASP3)

Alternative Name: CASP3 / Caspase 3

Background: Name/Gene ID: CASP3
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama

Gene ID: 836

UniProt: P42574

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation