CMA1 antibody

Catalog No. ABIN201286

This Mouse Monoclonal antibody specifically detects CMA1 in IHC. It exhibits reactivity toward Human.

Quick Overview for CMA1 antibody (ABIN201286)

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CMA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CMA1 Antibody

Specificity: Recognizes human mast cell chymase.

Purification: Ammonium sulfate precipitation

Immunogen: Purified Mast Cell Chymase from human skin.

Type of Immunogen: Purified protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: IHC (0.5 - 1 μg/mL)

Usage: Suitable for use in Immunohistochemistry. Not suitable for use in formaldehyde fixed tissue. Immunohistochemistry: 0.5-1 μg/mL. For optimal results, tissues or cytospin preparations should be fixed in Carnoy's Fluid (60 % ethanol, 30 % chloroform, 10 % glacial acetic acid).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 150 mM sodium chloride, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Alternative Name: CMA1 / MCT1 / Chymase

Background: Name/Gene ID: CMA1
Subfamily: Serine S1
Family: Protease

Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM

Gene ID: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis