IGFBP7 antibody

Catalog No. ABIN205804

This Rabbit Polyclonal antibody specifically detects IGFBP7 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IGFBP7 antibody (ABIN205804)

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGFBP7 Antibody

Specificity: Recognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumor types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol.

Purification: Purified

Immunogen: Recombinant human IGFBP-7.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 2 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: ELISA: LS-C42599 may be used in an indirect ELISA or as a capture reagent in sandwich ELISA.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.2.

Target Details for IGFBP7

Target: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Alternative Name: IGFBP7 / TAF

Background: Name/Gene ID: IGFBP7

Synonyms: IGFBP7, AGM, FSTL2, IGFBP-7v, IGFBP-rP1, IBP-7, Angiomodulin, RAMSVPS, MAC25 protein, PSF, TAF, Tumor-derived adhesion factor, IGF-binding protein 7, IGFBP-7, IGFBPRP1, MAC25, PGI2-stimulating factor

Gene ID: 3490

Pathways: Growth Factor Binding