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Antibodies
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anti-APAF1 / APAF-1 (AA 12-28) antibody
APAF1 / APAF-1 (AA 12-28) antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN205853 |
| Quantity |
100 µg (0.5 mg/ml) (Variants) |
| Price |
380.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Swiss-Prot
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O14727
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Immunogen
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Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 ( AA 12-28 ).
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Gene: APAF1 / APAF-1, Standard Gene Symbol: APAF1, Family: Apoptosis, Synonyms: APAF1, APAF-1, Apoptotic protease activating factor 1, CED4, DKFZp781B1145
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Specificity
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Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Recognizes a 130kD band in Western blots Predicted Reactivities: Mouse (Murine).
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Application Notes
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WB (1:1000 - 1:2000)
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Concentration
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0.5 mg/ml
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Purification
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Affinity Chromatography
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Buffer
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PBS, 0.02% sodium azide.
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Storage
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+4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
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Restrictions
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For Research Use only
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Alternatives for antigen "APAF1 / APAF-1 (AA 12-28)", type "Antibodies"
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