CD56 antibody

Catalog No. ABIN206684

The Mouse Monoclonal anti-CD56 antibody is suitable to detect CD56 in samples from Human. It has been validated for FACS, IHC, ELISA, IHC (p) and IHC (fro).

Quick Overview for CD56 antibody (ABIN206684)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CD56 Antibody

Specificity: Recognizes human neural cell adhesion molecule (NCAM), otherwise known as CD56. The CD56 Molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180kD form, while hemopoietic cells express the 140kD isoform. Antibodies produced by clone 123C3 recognize the 140 and 180kD isoforms of the CD56 protein. In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumors including tumors of the lung, neural derived malignancies and natural killer cell lymphomas.

Purification: Protein G purified

Immunogen: Small cell lung carcinoma.

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo (1:10), IHC, IHC-Fr, IHC-P (1:200, 10 μg/mL)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer  pH 6.0 is recommended for this purpose.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: NCAM / CD56

Background: Name/Gene ID: NCAM1
Family: Immunoglobulin

Synonyms: NCAM1, CD56, CD56 antigen, MSK39, NCAM-1, N-CAM-1, NCAM

Gene ID: 4684