TNC antibody

Catalog No. ABIN210680

The Mouse Monoclonal anti-TNC antibody is suitable to detect TNC in samples from Human. It has been validated for WB, IHC, ELISA, IP, IHC (p) and IHC (fro).

Quick Overview for TNC antibody (ABIN210680)

Target: TNC (Tenascin C (TNC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: T2H5

Product Details anti-TNC Antibody

Specificity: Clone T2H5 recognizes Tenascin in both normal and hyperproliferative (also neoplastic) tissues. Tenascin has been implicated in the guidance of migrating neurons and axons during development and neuronal regeneration. It promotes cortical neuron outgrowths and is an important component of the wound matrix and scar formation.

Purification: Protein A purified

Immunogen: Native Purified protein from human mammary tumor.

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (1:1000 - 1:2000), IHC, IHC-Fr, IHC-P, IP, WB

Usage: ELISA: This product is suitable for use in direct ELISA applications. Immunohistology: Staining may be enhanced using trypsin digestion or heat mediated antigen retrieval using sodium citrate buffer  pH 6.0.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris buffered saline, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for TNC

Target: TNC (Tenascin C (TNC))

Alternative Name: TNC / Tenascin C

Background: Name/Gene ID: TNC
Family: Fibronectin

Synonyms: TNC, 150-225, Cytotactin, GP, Hexabrachion (tenascin), GMEM, GP 150-225, Miotendinous antigen, Myotendinous antigen, JI, Tenascin, Tenascin C, Neuronectin, Tenascin-C isoform 14/AD1/16, TN-C, Hexabrachion, HXB, Tenascin-C, TN

Gene ID: 3371

UniProt: P24821

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development