P2RX6 antibody (AA 66-115)

Catalog No. ABIN6735763

This Rabbit Polyclonal antibody specifically detects P2RX6 in WB, IHC and IHC (p). It exhibits reactivity toward Human, Rat, Cow, Guinea Pig, Horse, Rabbit, Pig and Monkey.

Quick Overview for P2RX6 antibody (AA 66-115) (ABIN6735763)

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Rabbit, Pig, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-P2RX6 Antibody

Binding Specificity: AA 66-115

Specificity: Human P2RX6 / P2X6

Predicted Reactivity: Percent identity by BLAST analysis: Human, Bovine (100%) Mouse, Dog (92%) Rat, Chicken (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa66-115 of human P2RX6 (O15547, NP_005437). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Elephant, Bovine, Rabbit, Horse, Pig, Guinea pig (100%), Mouse, Dog (92%), Rat, Panda, Turkey, Chicken, Platypus (85%), Zebra finch (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (1.25 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 1.25 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for P2RX6

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Alternative Name: P2RX6 / P2X6

Background: Name/Gene ID: P2RX6
Subfamily: P2X receptor
Family: Ion Channel

Synonyms: P2RX6, ATP receptor, p2RXL1, p2X purinoceptor 6, p2RX6, p2X6, p2X6 purinoceptor, p2XM, Purinergic receptor, Purinoreceptor P2X6, Skeletal muscle-expressed P2X, p2X receptor 6, p2X-like 1, Purinergic receptor P2X-like 1, Purinoceptor P2X6

Gene ID: 9127

NCBI Accession: NP_005437

UniProt: O15547