LRP1 antibody

Catalog No. ABIN215051

The Mouse Monoclonal anti-LRP1 antibody is suitable to detect LRP1 in samples from Human. It has been validated for WB, IHC, FACS and IF.

Quick Overview for LRP1 antibody (ABIN215051)

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-LRP1 Antibody

Specificity: Specifically recognizes the 515kD a-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. Can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91).

Purification: Protein A purified

Immunogen: Human LRP/a2MR.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IF, IHC (1:20), WB

Usage: Suitable for use in Immunofluorescence, Immunohistochemistry, Flow Cytometry and Western Blot. Immunohistochemistry: 1:20.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile 40-50 % glycerol, ddH2O

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 0.5 % BSA.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LRP1

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Alternative Name: LRP1 / CD91

Background: Name/Gene ID: LRP1

Synonyms: LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1

Gene ID: 4035

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling