ADAM17 antibody (C-Term)

Catalog No. ABIN6757224

This Rabbit Polyclonal antibody specifically detects ADAM17 in WB and ELISA. It exhibits reactivity toward Rat and Mouse.

Quick Overview for ADAM17 antibody (C-Term) (ABIN6757224)

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM17 Antibody

Binding Specificity: C-Term

Specificity: The rat peptide sequence is 100 % conserved in mouse and 99 % in human TACE. No significant sequence homology exists with other proteases. Antibody cross-reactivity in various species is not established.

Purification: Immunoaffinity purified

Immunogen: A 17 aa peptide near the C-terminus of rat TACE (1) conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, WB (1 - 10 μg/mL)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1-10 μg/mL using ECL.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA, 0.1 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for ADAM17

Target: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Alternative Name: ADAM17 / TACE

Background: Name/Gene ID: ADAM17
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM17, CD156B, CD156b antigen, CSVP, ADAM 17, NISBD, TNF-alpha converting enzyme, TNF-alpha convertase, TNF-alpha-converting enzyme, Snake venom-like protease, TACE

Gene ID: 6868

UniProt: P78536

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus