Topoisomerase I antibody

Catalog No. ABIN6757606

The Mouse Monoclonal anti-Topoisomerase I antibody is suitable to detect Topoisomerase I in samples from Human. It has been validated for WB.

Quick Overview for Topoisomerase I antibody (ABIN6757606)

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Topoisomerase I antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Topoisomerase I Antibody

Specificity: Recognizes human topoisomerase I. No reactivity is seen with topoisomerase II alpha or beta proteins.

Purification: Immunoaffinity purified

Immunogen: Purified human Topoisomerase I protein.

Isotype: IgG1

Application Details

Application Notes: Approved: WB (1 - 5 μg/mL)

Usage: Suitable for use in Western Blot. Western Blot: 1-5 μg/mL. Human kidney topoisomerase I is ~100kD.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide, 40 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Topoisomerase I

Target: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Alternative Name: TOP1 / Topoisomerase I

Background: Name/Gene ID: TOP1
Family: Topoisomerase

Synonyms: TOP1, DNA topoisomerase I, DNA topoisomerase 1, TOPI, Topoisomerase (DNA) I, Topoisomerase I, Type I DNA topoisomerase

Gene ID: 7150

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance