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Acid Phosphatase, Prostate (ACPP) antibody

Antigen

Acid Phosphatase, Prostate (ACPP)

Synonyms PAP, ACP3, ACP-3, Lap, Ppal, AI324033, A030005E02Rik, pap, Acpp11, RNACPP11, ACPP, MGC159906, acpt, MGC130636
Clonality Monoclonal (LT-3D1)
Host
Alternatives

Mouse

Reactivity
Alternatives

Human

Application
Alternatives Flow Cytometry (FACS), Cell-ELISA (cELISA)
Catalog no. ABIN238332
Quantity 100 ug  (2mg/ml)
Price 594.29 $   Plus shipping costs $35.00
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Availability Ships within 3 to 5 Business Days

Additional Information

Alternative name Prostatic Acid Phosphatase (PAP)
Swiss-Prot P15309
Immunogen genetic immunisation with cDNA encoding human PAP (Sequence: AAH07460)
Format Purified
Isotype IgG1  (Matching secondary antibodies)
Clone LT-3D1
Description Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each. It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH. Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland.

Application Details

Application Notes Flow cytometry: 1.2 μg/10^6 cells. CELISA: 1:200 - 1:400
Concentration 2mg/ml
Purification The antibody was purified by protein G affinity chromatography from cell culture supernatants and verified by SDS-Page
Buffer phosphate buffered saline, pH 7.2
Research Area Cancer
Restrictions For Research Use only