Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS) antibody

Antigen: Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS)

Synonyms: GAS, MPS4A, FLJ17434, FLJ42844, FLJ98217, GALNAC6S, FLJ00319, mFLJ00319, Galns, GALNS

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN238565

Additional Information

Alternative name: GALNS

Gene ID: 2588

Immunogen: C-TTHNLEDHTKLP

Format: Affinity-purified

Description: All names and symbols: GALNS, galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA), GALNAC6S, GAS, MPS4A, N-acetylgalactosamine-6-sulfatase, chondroitinase. Official Symbol: GALNS. RefSeq number(s): NP_000503.1

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx 60kDa band observed in Human Bone Marrow and Placenta lysates (calculated MW of 58.0kDa according to NP_000503.1). Recommended concentration: 0.01-0.03µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Proteolysis / Ubiquitin, Extracellular Matrix, Organelles

Restrictions: For Research Use only

Images

ABIN238565 (0.01µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Houle, Tom, Mayes et al.: "Combining an autologous peripheral nervous system "bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 28, pp. 7405-15, 2006 (PubMed).