Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) antibody

Antigen: Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R)

Synonyms: ACTHR, MGC125798, LOC443482, Mc2r, MC2-R

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN238653

Additional Information

Alternative name: MC2R / ACTHR

Gene ID: 4158

Immunogen: ENINNTARNNSDC

Format: Affinity-purified

Description: All names and symbols: MC2R, ACTHR, melanocortin 2 receptor (adrenocorticotropic hormone), MGC125798, ACTH receptor, MC2 receptor, adrenocorticotropic hormone receptor, corticotropin receptor, melanocortin 2 receptor. Official Symbol: MC2R . RefSeq number(s): NP_000520.1

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 40kDa band observed in Human Skin lysates (calculated MW of 33.9kDa according to NP_000520.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Kilianova et al, Endocrinology. 2006 May,147(5):2325-37, PMID: 16497811). Recommended concentration: 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN238653 (1µg/ml) staining of Human Skin lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Kilianova, Basora, Kilian et al.: "Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization." in: Endocrinology, Vol. 147, Issue 5, pp. 2325-37, 2006 (PubMed).