ABCB1 antibody (Extracellular)
Quick Overview for ABCB1 antibody (Extracellular) (ABIN2450190)
Target
See all ABCB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Extracellular
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Brand
- IHC-plus™
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Specificity
- Extracellular amino terminal half This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to P-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of P-glycoprotein, respectively.
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Purification
- Protein G purified
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Immunogen
- Human and hamster drug-resistant viable cells followed by crude plasma membranes.
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Isotype
- IgG1
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Application Notes
- Approved: Flo, IF, IHC, IHC-P (20 μg/mL), WB (1 - 2 μg/mL)
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Comment
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Target Species of Antibody: Hamster
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Stable for 2 years when stored at 2-8°C.
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- ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
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Alternative Name
- ABCB1 / MDR1 / P Glycoprotein
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Background
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Name/Gene ID: ABCB1
Subfamily: ATP-binding cassette - ABCB/MDR
Family: Transporter
Synonyms: ABCB1, ABC20, Abcb1b, CLCS, Colchicin sensitivity, CD243, Doxorubicin resistance, IBD13, gp170, MDR1, Multidrug resistance protein 1, P glycoprotein, P-glycoprotein 1, P-GP, CD243 antigen, PGY1 -
Gene ID
- 5243
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UniProt
- P08183
Target
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