Cyclin D2 (CCND2) antibody

Details for Product No. ABIN264332
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Antigen
Synonyms si:ch211-240j22.2, ccnd2, CCND2, kiak0002, zgc:162280, LOC100224096, KIAK0002, 2600016F06Rik, AI256817, BF642806, C86853, Vin-1, Vin1, cD2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(118), (54), (40), (1), (1), (1)
Host
Mouse
(70), (52)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(94), (33), (32), (25), (17), (14), (10), (10), (9), (7), (6), (5), (3), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN264332
324.50 $
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Immunogen His-tagged recombinant full length Cyclin D2 protein recognizing a 34 kD protein.
Clone DCS-3-1
Isotype IgG2a
Characteristics Synonyms: Cyclin-D2, CCND2
Purification Affinity chromatography on Protein A/G
Alternative Name Cyclin D2
Background Cyclin D2 is a G1 cyclin required for a G1 phase progression. Like Cyclin D1, it is activated bythe same mechanisms. It is well suited for neutralization of Cyclin D2 activity in vivo.
UniProt P30279
Research Area Cancer, Cell Cycle
Application Notes Western Blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Frozen Sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS 0.08% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Expiry Date 12 months
Background publications Lukas, Bartkova, Welcker et al.: "Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types." in: Oncogene, Vol. 10, Issue 11, pp. 2125-34, 1995 (PubMed).

Bartkova, Lukas, Müller et al.: "Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer." in: Cancer research, Vol. 55, Issue 4, pp. 949-56, 1995 (PubMed).

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