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Antibodies
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anti-Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 183-201) antibody
Chemokine (C-C Motif) Receptor 8 (CCR8) (AA 183-201) antibody
| Antigen |
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| Synonyms |
CY6, TER1, CKRL1, CDw198, CKR-L1, CMKBR8, CMKBRL2, GPR-CY6, MGC129966, MGC129973 |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN265001 |
| Quantity |
100 µg (Lot specific) |
| Price |
310.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, GPR-CY6, Chemokinereceptor-like 1, TER1, CMKBRL2, CC-chemokine receptor CHEMR1, CKRL1, CMKBR8
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Alternative name
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CDw198 / CCR8
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Swiss-Prot
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P51685
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Immunogen
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Antibody raised against a synthetic peptide corresponding to amino acids 183 to 201 of thehuman CCR8. Peptide sequence is located in the second extracellular loop.
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Cross-Reactivity
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Human
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Isotype
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IgG (Matching secondary antibodies)
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Description
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CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1,and ChemR11-4. The encoded seven transmembrane protein was identified as the receptorfor human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as acoreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains5. CCR8mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelopefusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
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Specificity
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This antibody reacts to CCR8. Species: Human. Others not tested.
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Application Notes
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Western Blot: 0.5 to 1 ug/ml. Detects an approximately 50 kDa band in human spleentissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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Lot specific
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Purification
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Purified
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Buffer
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Phosphate buffered saline solution containing 0.02% sodium azide as apreservative
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Storage
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The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8C. DO NOT FREEZE! Shelf life: one year from despatch.
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Research Area
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Chemokines, Receptors
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-C Motif) Receptor 8 (CCR8)", type "Antibodies"
Alternatives 
