SAMD8 antibody

Catalog No. ABIN265117

This Rabbit Polyclonal antibody specifically detects SAMD8 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for SAMD8 antibody (ABIN265117)

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMD8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SAMD8 Antibody

Specificity: This antibody reacts to Sphingomyelin synthase-related protein 1.

Purification: Purified

Immunogen: Full-length recombinant sphingomyelin synthase r fusion protein.

Application Details

Application Notes: ELISA. Western Blot: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for SAMD8

Target: SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))

Alternative Name: SAMD8 / SMSr

Background: Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SAM domain-containing protein 8, Sphingomyelin synthase-related protein 1, Sterile alpha motif domain-containing protein 8

Gene ID: 142891

NCBI Accession: NP_653261

UniProt: Q96LT4