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CSF1R antibody (PerCP-Cy5.5)

CSF1R Reactivity: Human FACS Host: Rat Monoclonal 9-4D2-1E4 PerCP-Cy5.5
Catalog No. ABIN2659933
  • Target See all CSF1R Antibodies
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Reactivity
    • 183
    • 107
    • 74
    • 17
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 199
    • 19
    • 15
    • 3
    • 2
    • 1
    Rat
    Clonality
    • 200
    • 38
    • 1
    Monoclonal
    Conjugate
    • 97
    • 23
    • 13
    • 11
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    This CSF1R antibody is conjugated to PerCP-Cy5.5
    Application
    • 148
    • 93
    • 87
    • 58
    • 39
    • 26
    • 22
    • 21
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.
    Clone
    9-4D2-1E4
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CSF1R Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Alternative Name
    CD115 (CSF1R Products)
    Background
    CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitinylation of intracellular residues. The natural ligands of CD115 include M-CSF and IL-34. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, plasmacytoid and conventional dendritic cells, and osteoclasts.
    Pathways
    RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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