CSF1R antibody (Colony Stimulating Factor 1 Receptor) (AA 344-497)

Details for Product anti-CSF1R Antibody No. ABIN1724928, Supplier: Log in to see
Antigen
  • AI323359
  • CD115
  • CSF-1R
  • Csfmr
  • Fim-2
  • Fms
  • M-CSF-R
  • M-CSFR
  • C-FMS
  • CSFR
  • FIM2
  • FMS
  • HDLS
  • PDGFRB
  • MGC89146
  • CSF-1-R
  • c-fms
  • mrfms
  • CSF1
  • M-CSF
  • csf1r
  • fms
  • panther
  • colony stimulating factor 1 receptor
  • macrophage colony-stimulating factor receptor
  • colony stimulating factor 1 receptor, a
  • Csf1r
  • CSF1R
  • m-csfr
  • csf1r
  • csf1ra
Alternatives
anti-Human CSF1R antibody for Immunocytochemistry
Epitope
AA 344-497
39
30
24
22
18
15
15
15
14
12
10
10
9
8
7
7
7
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
375
254
110
23
12
9
8
6
5
4
3
3
2
2
1
Host
Mouse
261
141
106
34
3
Clonality (Clone)
Monoclonal ()
Conjugate
This CSF1R antibody is un-conjugated
35
31
29
29
18
13
11
9
8
8
8
7
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6
5
5
5
5
5
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
343
269
224
186
92
63
26
16
16
13
8
7
7
4
3
3
3
3
3
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human CSF1R (AA 344-497) expressed in E. Coli.
Clone 6B9H2
Isotype IgG2b
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others CSF1R products on genomics-online (e.g. as negative or positive controls)
Antigen Colony Stimulating Factor 1 Receptor (CSF1R)
Alternative Name CSF1R (CSF1R Antibody Abstract)
Background The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. ,
Molecular Weight 108 kDa
Gene ID 1436
HGNC 1436
Pathways RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody
Flow Cytometry (FACS) image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (Image 2)
Western Blotting (WB) image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (Image 3)
Western Blotting (WB) image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (Image 4)
Immunohistochemistry (IHC) image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using CSF1R...
Immunohistochemistry (IHC) image for anti-Colony Stimulating Factor 1 Receptor (CSF1R) (AA 344-497) antibody (ABIN1724928) Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CSF1R...
Product cited in: Morandi, Barbetti, Riverso, Dello Sbarba, Rovida: "The colony-stimulating factor-1 (CSF-1) receptor sustains ERK1/2 activation and proliferation in breast cancer cell lines." in: PLoS ONE, Vol. 6, Issue 11, pp. e27450, 2011 (PubMed).

Kitagawa, Gouda, Kirii, Sugiyama, Ishihama, Fujii, Narumi, Akita, Yokota: "Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase." in: Journal of biochemistry, Vol. 151, Issue 1, pp. 47-55, 2011 (PubMed).

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