CD137 antibody (PerCP-Cy5.5)

Catalog No. ABIN2660273

The PerCP-Cy5.5-conjugated Mouse Monoclonal anti-CD137 antibody (Clone 4B4-1) (ABIN2660273) specifically detects CD137 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD137 antibody (PerCP-Cy5.5) (ABIN2660273)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD137 antibody is conjugated to PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: 4B4-1

Product Details anti-CD137 Antibody (PerCP-Cy5.5)

Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey

Purification: The antibody was purified by affinity chromatography, and conjugated with PerCP/Cy5.5 under optimal conditions. The solution is free of unconjugated PerCP/Cy5.5 and unconjugated antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: CD137

Background: CDw137 is a 39 kD transmembrane protein also known as 4-1BB. It is expressed on activated T cells. CDw137 is a type I membrane protein and a member of the tumor necrosis factor receptor superfamily. CDw137 appears to be important for T cell proliferation and survival, and induces monocyte activation through its interaction with 4-1BB ligand.

Pathways: Cancer Immune Checkpoints