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- Target See all NGFR Antibodies
- NGFR (Nerve Growth Factor Receptor (NGFR))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NGFR antibody is conjugated to PE
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Application
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- Cross-Reactivity
- Monkey, Raccoon (Procyon lotor), Sheep (Ovine), Cat (Feline), Dog (Canine), Pig (Porcine), Rabbit
- Purification
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- ME20-4
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product NGFR Primary Antibody
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anti-Nerve Growth Factor Receptor (NGFR) (AA 301-400) antibody
NGFR Reactivity: Human, Rat, Mouse WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Rat WB, ELISA, IHC Host: Mouse Monoclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal NGFR-1964 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 188-203), (Extracellular), (Stalk Region) antibodyNGFR Reactivity: Human, Rat, Mouse WB, FACS, IF, IHC, ICC, IP, LCI Host: Rabbit Polyclonal unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate, Rabbit, Cat, Ferret WB, FACS, IHC (p), ICC, IP, CyTOF Host: Mouse Monoclonal NGFR5 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human FACS, ELISA, ICC Host: Mouse Monoclonal 2F1C2 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) (AA 281-421) antibodyNGFR Reactivity: Human IHC, Diff, StM Host: Mouse Monoclonal rNGFR-1965 unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Non-Human Primate IHC, Diff, StM Host: Rabbit Monoclonal NGFR-1997R unconjugated Recombinant Antibody
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, ELISA, IHC Host: Mouse Monoclonal 8G3G10 unconjugated
anti-Nerve Growth Factor Receptor (NGFR) antibodyNGFR Reactivity: Human, Mouse WB, IF, IHC (p) Host: Mouse Monoclonal 8G3G10 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Alternative Name
- CD271 (NGFR Products)
- Background
- CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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