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CD25 antibody (Alexa Fluor 488)
IL2RA
Reactivity: Human
FACS, IHC, IF
Host: Mouse
Monoclonal
BC96
Alexa Fluor 488
Product Details anti-CD25 Antibody (Alexa Fluor 488)
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Target
See all CD25 (IL2RA) Antibodies
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Reactivity
All reactivities for CD25 antibodies
Human
Host
All hosts for CD25 antibodies
Mouse
Clonality
All clonalities for CD25 antibodies
Monoclonal
Conjugate
All conjugates for CD25 antibodies
This CD25 antibody is conjugated to Alexa Fluor 488
Application
All applications for CD25 antibodies
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Baboon, Chimpanzee, Cynomolgus, Rhesus Monkey, Pigtailed Macaque
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone
BC96
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD25
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Target
CD25 (IL2RA)
(Interleukin 2 Receptor, alpha (IL2RA))
Alternative Name
CD25 (IL2RA Products )
Background
CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.
Pathways
JAK-STAT Signaling , Growth Factor Binding , Activated T Cell Proliferation
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