GPR77 antibody

Catalog No. ABIN2664089

The Mouse Monoclonal anti-GPR77 antibody (Clone 1D9-M12) (ABIN2664089) specifically detects GPR77 in FACS. The antibody is reactive with Human samples.

Quick Overview for GPR77 antibody (ABIN2664089)

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR77 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 1D9-M12

Product Details anti-GPR77 Antibody

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Alternative Name: C5L2

Background: C5L2 (C5a receptor-like 2) is a seven-transmembrane orphan receptor, also known as GPR77, which shares significant homology to C5a receptor (CD88), but it is a decoy receptor without G-protein coupling. C5L2 is co-expressed with C5aR on many kinds of cells, such as neutrophils, immature dendritic cells, mast cells, macrophages, and astrocytes. C5L2 binds C5a with similar high affinity as C5aR and relatively higher affinity for C5a-des-Arg than with C5aR.