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Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA) antibody

Antigen

Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA)
Synonyms LT, TNFB, TNFSF1, Ltx, Tnfb, LT[a], LT-[a], hlb382, LTalpha, Tnfsf1b, LT-alpha, TNF-beta, MGC117668, LT-a, tnfb, tnfsf1, LTA
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
Catalog no. ABIN272216
Quantity 100 µg  (1,0 mg/ml)  (Variants)
Price 340.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: TNFB, TNFSF1, LTA, LT-alpha, Tumor necrosis factor ligand superfamily member 1
Alternative name TNF-beta / Lymphotoxin-alpha
Swiss-Prot P01374
Cross-Reactivity Human, Mouse (Murine)
Description Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha, also known as TNF−beta) aremembers of a family of secreted and cell surface cytokines that participate in theregulation of immune and inflammatory responses. LT-beta (lymphotaxin-beta or tumornecrosis factor C) is a type II membrane protein with significant homology to TNF, LT-alpha,and the ligand for the CD40 receptor. LT-alpha is present on the surface of activated T, B,and LAK cells as a complex with the 33 kda glycoprotein, LT-beta. LT-beta, also expressedby active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchorsLT-alpha to the cell surface. A TNF receptor-related protein, the LT-beta receptor (alsoknown as TNFC receptor), is the human receptor for the LT-alpha/LT-beta heterotrimer. There are two LT-beta isoforms expressed in human lymphoid cell lines and non-Hodgkin'slymphomas. The gene which encodes LT-beta maps to the major histocompatibilitycomplex region on human chromosome 6p21. 3.
Specificity LT-beta (V211) antibody detects endogenous levels of LT-beta protein. Species: Human, Mouse . Others not tested.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes ELISA: 1: 10000~1: 20000. WB: 1: 500~1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1,0 mg/ml
Purification Aff - Purified
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Research Area Cytokines, Growth Factors, Receptors, Immunology, Inflammation
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Lymphotoxin alpha (TNF Superfamily, Member 1) (LTA)", type "Antibodies"
Hosts Rabbit (35), Mouse (5), Sheep (1)
Reactivities Human (39), Mouse (Murine) (20), Rat (Rattus) (20), Cow (Bovine) (15), Dog (Canine) (15), Horse (Equine) (15), Rabbit (15)
Applications Immunofluorescence (IF) (22), Western Blotting (WB) (21), Flow Cytometry (FACS) (20), Enzyme Immunoassay (EIA) (9), ELISA (6), Blocking Antibody (Inhibition) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Functional Studies (Func) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Neutralization (Neut) (1)
Conjugates Biotin (3), FITC (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes Center (1)