CXCR6 antibody (AA 11-25)

Catalog No. ABIN272373

The Rabbit Polyclonal anti-CXCR6 antibody (ABIN272373) specifically detects CXCR6 in WB. The antibody is reactive with Human samples.

Quick Overview for CXCR6 antibody (AA 11-25) (ABIN272373)

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXCR6 Antibody

Binding Specificity: AA 11-25

Purification: Purified

Immunogen: Synthetic peptide corresponding to amino acids 11 to 25 of the human Bonzo protein.

Isotype: IgG

Application Details

Application Notes: Western Blot: Detects Bonzo protein at 0.5 to 1 μg/mL (approx. 45 kDa band in human spleen tissue lysate). Positive Control: Human spleen tissue lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % Sodium Azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. Do Not Freeze!
Shelf Life: One year from despatch.

Expiry Date: 12 months

Target Details for CXCR6

Target: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Alternative Name: CD186 / CXCR6

Background: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as an HIV and SIV coreceptor (1-4). Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR

Gene ID: 10663

UniProt: O00574