LTK antibody (AA 800-864)

Catalog No. ABIN292876

This Rabbit Polyclonal antibody specifically detects LTK in WB, IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for LTK antibody (AA 800-864) (ABIN292876)

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LTK Antibody

Binding Specificity: AA 800-864

Specificity: The amino acid sequence used as immunogen has 100 % identity in human isoforms 1 and 2, and 81 % homologous in mouse isoforms A, B, C, and D, and rat. LTK is an 864 amino acid protein with an approximate molecular weight of 94 kD.

Purification: Protein G purified

Immunogen: Synthetic peptide from human LTK.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), WB (0.5 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for LTK

Target: LTK (Leukocyte Receptor tyrosine Kinase (LTK))

Alternative Name: LTK

Background: Name/Gene ID: LTK
Subfamily: LTK/ALK

Synonyms: LTK, Leukocyte tyrosine kinase, Protein tyrosine kinase 1, TYK1

Gene ID: 4058

UniProt: P29376

Pathways: RTK Signaling