FNTA antibody (AA 150-250)

Catalog No. ABIN298038

The Rabbit Polyclonal anti-FNTA antibody (ABIN298038) specifically detects FNTA in WB, IHC and IHC (p). The antibody is reactive with Human, Rat, Mouse, Dog and Chicken samples.

Quick Overview for FNTA antibody (AA 150-250) (ABIN298038)

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reactivity: Human, Rat, Mouse, Dog, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FNTA Antibody

Binding Specificity: AA 150-250

Specificity: The amino acid sequence used as immunogen is 100 % homologous in human (isoforms CRA_a, _b, _c), rat, dog, chicken, and chimp (isoforms 1, 2, 3), and 93 % homologous in mouse.

Purification: Protein G purified

Immunogen: A portion of amino acids 150-250 of human farnesyltransferase.

Type of Immunogen: Protein fragment

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (10 μg/mL), WB (1 - 3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Alternative Name: PTAR2 / FNTA

Background: Name/Gene ID: FNTA

Synonyms: FNTA, FPTA, FTase-alpha, GGTase-I-alpha, PTAR2, PGGT1A

Gene ID: 2339

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling