FNTA antibody (AA 329-379)

Catalog No. ABIN7455017

The Rabbit Polyclonal anti-FNTA antibody (ABIN7455017) specifically detects FNTA in WB, IP and IHC (fp). The antibody is reactive with Human samples.

Quick Overview for FNTA antibody (AA 329-379) (ABIN7455017)

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-FNTA Antibody

Binding Specificity: AA 329-379

Purpose: Rabbit anti-FNTA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 329 and 379

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Alternative Name: FNTA

Background: Background: Farnesyl-protein transferase alpha-subunit (FNTA) catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity) [taken from the Universal Protein Resource (UniProt) P49354].

Gene ID: 2339

NCBI Accession: NP_002018

UniProt: P49354

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling