DcR2 antibody (AA 1-210)
Quick Overview for DcR2 antibody (AA 1-210) (ABIN301992)
Target
See all DcR2 (TNFRSF10D) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-210
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Purpose
- Anti-Hu CD264 Purified Azide Free
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Cross-Reactivity (Details)
- Human
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Characteristics
- The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
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Purification
- Purified by protein-A affinity chromatography.
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Purity
- > 95 % (by SDS-PAGE)
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Immunogen
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
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Isotype
- IgG1
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibodyTNFRSF10D Reactivity: Human, Monkey WB, ELISA Host: Mouse Monoclonal 7G7H9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibodyTNFRSF10D Reactivity: Human, Mouse WB, ELISA Host: Mouse Monoclonal 6G7G1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibodyTNFRSF10D Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (FITC)TNFRSF10D Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R4-01 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 252-278) antibodyTNFRSF10D Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24080 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibodyTNFRSF10D Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivity: Human WB, FACS Host: Rabbit Monoclonal 23GB4685 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibodyTNFRSF10D Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4
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Preservative
- Azide free
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Handling Advice
- Do not freeze
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
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Alternative Name
- CD264
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Background
- TNF receptor superfamily member 10d,TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).,TNFRSF10D, DcR2, TRUNDD, TRAILR4
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Gene ID
- 8793
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UniProt
- Q9UBN6
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Pathways
- Apoptosis
Target
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