DcR2 antibody (AA 257-386)

Catalog No. ABIN7173838

The Rabbit Polyclonal anti-DcR2 antibody (ABIN7173838) specifically detects DcR2 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for DcR2 antibody (AA 257-386) (ABIN7173838)

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DcR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DcR2 Antibody

Binding Specificity: AA 257-386

Purpose: TNFRSF10D Antibody

Cross-Reactivity: Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Tumor necrosis factor receptor superfamily member 10D protein (257-386AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DcR2

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Alternative Name: TNFRSF10D

Background:

Background: Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

Aliases: CD 264 antibody, CD264 antibody, DcR 2 antibody, DcR2 antibody, Decoy receptor 2 antibody, Decoy with truncated death domain antibody, OTTHUMP00000123528 antibody, TNF receptor related receptor for TRAIL antibody, TNF related apoptosis inducing ligand receptor 4 antibody, TNF-related apoptosis-inducing ligand receptor 4 antibody, TNFRSF 10D antibody, TNFRSF10D antibody, TR10D_HUMAN antibody, TRAIL R4 antibody, TRAIL receptor 4 antibody, TRAIL receptor with a truncated death domain antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, Tumor necrosis factor receptor superfamily member 10D antibody, Tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain antibody

UniProt: Q9UBN6

Pathways: Apoptosis