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Integrin alpha X (ITGAX) antibody
| Antigen | Integrin alpha X (ITGAX) |
| Synonyms |
CD11C, SLEB6, BR, GPIa, CD49B, VLA-2, VLAA2, VL3A, CD49C, GAPB3, MSK18, VCA-2, VLA3a, GAP-B3, FLJ34631, FLJ34704, IA4, CD49D, MGC90518, FNRA, CD49e, VLA5A, ITGAX, RGD1561123, Cr4, N418, Cd11c, AI44940 ...
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| Clonality | Monoclonal (BU15) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human, Dog (Canine), Monkey |
| Application |
Alternatives Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
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| Catalog no. | ABIN302095 |
| Quantity | 0.1 mg (1 mg/ml) |
| Price | 273.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 3 to 5 Business days |
Additional Information
| Alternative name | CD11c |
| Immunogen | Dendritic cells of synovial fluid |
| Format | Purified |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | BU15 |
| Description | CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit)and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds tocomplement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interactionof CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparincounteracts binding of iC3b. |
| Specificity | The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainlyon dendritic cells and tissue macrophages.HLDA III, WS Code M 256HLDA V, WS Code AS S143HLDA VI, WS Code AS Ref.6 |
| Synonyms | CD11C, SLEB6, BR, GPIa, CD49B, VLA-2, VLAA2, VL3A, CD49C, GAPB3, MSK18, VCA-2, VLA3a, GAP-B3, FLJ34631, FLJ34704, IA4, CD49D, MGC90518, FNRA, CD49e, VLA5A, ITGAX, RGD1561123, Cr4, N418, Cd11c, AI449405, CD11c |
Application Details
| Concentration | 1 mg/ml |
| Purity | > 95% (by SDS-PAGE) |
| Purification | Purified from ascites by protein-A affinity chromatography. |
| Buffer | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage | Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles. |
| Research Area | Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells |
| Restrictions | For Research Use only |
Images
| Surface staining of human peripheral blood cells with anti-CD11c (BU15) PerCP (monocyte gate). |
Alternatives
Alternatives for antigen "Integrin alpha X (ITGAX)", type "Antibodies"
| Hosts | Mouse (133), Rat (52), Hamster (27), Rabbit (24) |
| Reactivities | Human (146), Mouse (Murine) (86), Rat (Rattus) (30), Monkey (25), Dog (Canine) (16), Cow (Bovine) (4), Pig (Porcine) (3), Rabbit (1) |
| Applications | Flow Cytometry (FACS) (197), Immunohistochemistry (Frozen Sections) (IHC (fro)) (68), Immunoprecipitation (IP) (41), Western Blotting (WB) (31), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20), Enzyme Immunoassay (EIA) (15), Functional Studies (Func) (11), Immunofluorescence (IF) (11), ELISA (7), Immunohistochemistry (IHC) (2), ELISA (Detection) (1) |
| Conjugates | FITC (42), Biotin (26), PE (23), RPE (4), Alexa Fluor 647 (2), APC (1), Alexa Fluor 488 (1), Pacific Blue (1), PerCP (1) |
| Epitopes | C-Term (5), internal (2), p150:95a (1) |
