GTP Cyclohydrolase 1 (GCH1) antibody

Antigen: GTP Cyclohydrolase 1 (GCH1)

Synonyms: GCH, DYT5, DYT14, DYT5a, GTPCH1, HPABH4B, GTP-CH-1, GCH1, Gch, GTPCH, GTP-CH, MGC89622, zgc:195269

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN302137

Additional Information

Alternative name: GCH1

Gene ID: 2643, 14528 (mouse), 29244 (rat)

Immunogen: Peptide with sequence C-GKVHIGYLPNKQ, from the internal region of the protein sequence according to NP_000152.1 , NP_001019195.1 , NP_001019241.1 , NP_001019242.1

Format: Affinity-purified

Description: All names and symbols: GCH1 , GTP cyclohydrolase 1 (dopa-responsive dystonia) , DYT5, GCH, GTP-CH-1, GTPCH1, GTP cyclohydrolase 1, guanosine 5'-triphosphate cyclohydrolase I. Official Symbol: GCH1. RefSeq number(s): NP_000152.1 , NP_001019195.1 , NP_001019241.1 , NP_001019242.1.

Specificity: Expected from sequence similarity: Human, Mouse, Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 37kDa band observed in Human Lymph Node, Thymus and Tonsil lysates. Customer’s experiments gave identical results in lysates of cell line HUVEC with antibodies raised against different parts of the same protein. (calculated MW of 27.9kDa according to NP_000152.1). Recommended concentration: 1-3µg/ml.

Concentration: 100µg specific antibody in 200µl

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only