Formyl Peptide Receptor 2 (FPR2) (AA 13-26) antibody

Antigen: Formyl Peptide Receptor 2 (FPR2)

Synonyms: ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, Fpr-rs2, MGC151443, E330010I07Rik, FPR2, Fprl1, ALX, Lxa4r, LXA4-R, Fpr-rs1, FMLP-R-I

Epitope: AA 13-26

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN302146

Additional Information

Alternative name: FPRL1 (aa13-26)

Gene ID: 2358

Immunogen: EEVSYESAGYTVLR-C

Format: Affinity-purified

Description: All names and symbols: FPRL1, formyl peptide receptor-like 1 , ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, HM63, LXA4R, lipoxin A4 receptor (formyl peptide receptor related). Official Symbol: FPRL1. RefSeq number(s): NP_001005738.1, NP_001453.1

Specificity: This antibody is expected to recognize both reported isoforms (NP_001005738.1, NP_001453.1) which are identical. Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Preliminary experiments gave an approx. 49kDa band in Human Peripheral Blood Mononucleocytes, and Cell line U93l7 lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 39.0kDa according to NP_001453.1. The 49kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Mitchell, OMeara, Gaffney et al.: "The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15606-18, 2007 (PubMed).