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FPR2 antibody (AA 51-150)

FPR2 Reactivity: Human, Mouse, Rat ELISA, FACS, IF (cc), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1 reference)
Catalog No. ABIN702175
$384.62
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target See all FPR2 Antibodies
    FPR2 (Formyl Peptide Receptor 2 (FPR2))
    Binding Specificity
    • 15
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    Human, Mouse, Rat
    Host
    • 32
    • 14
    • 11
    Rabbit
    Clonality
    • 47
    • 10
    Polyclonal
    Conjugate
    • 25
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FPR2 antibody is un-conjugated
    Application
    • 25
    • 17
    • 16
    • 12
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)
    Specificity
    Possible cross-reactivity with FPR1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FPRL1
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Diao, Zhang, Chen, Yuan, Lee, Geng, Kowalski, Guo, Xiong, Li, Li: "Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis." in: Scientific reports, Vol. 6, pp. 34672, (2016) (PubMed).

  • Target
    FPR2 (Formyl Peptide Receptor 2 (FPR2))
    Alternative Name
    FPRL1/Lipoxin A4 receptor (FPR2 Products)
    Synonyms
    ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody
    Background

    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

    Subcellular location: Cell membrane

    Synonyms: ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2

    Gene ID
    2358
    UniProt
    P25090
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