Serotonin Receptor 5A antibody (1st Extracellular Domain, Extracellular Domain)

Catalog No. ABIN302361

The Rabbit Polyclonal anti-Serotonin Receptor 5A antibody (ABIN302361) specifically detects Serotonin Receptor 5A in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Serotonin Receptor 5A antibody (1st Extracellular Domain, Extracellular Domain) (ABIN302361)

Target: Serotonin Receptor 5A (HTR5A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 5A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Serotonin Receptor 5A Antibody

Binding Specificity: 1st Extracellular Domain, Extracellular Domain

Specificity: This antibody detects 5-HT5A Receptor (HTR5A).

Cross-Reactivity (Details): Species reactivity (expected):Human (100 %), Gorilla (100 %), Gibbon (100 %), Monkey (100 %), Marmoset (100 %), Mouse (100 %), Rat (100 %), Bovine (100 %), Dog (100 %), Elephant (100 %), Panda (100 %), Horse (100 %), Guinea pig (100 %), Opossum (94 %), Turkey (89 %), Chicken (89 %), Lizard (83 %), Zebrafish (83 %), Stickleback (83 %).
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: HTR5A antibody was raised against synthetic peptide from 1st extracellular domain of human HTR5A / 5-HT35A.

Application Details

Application Notes: ELISA. Immunohistochemistry on Paraffin Section (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for Serotonin Receptor 5A

Target: Serotonin Receptor 5A (HTR5A)

Background: This is one of the several different receptors for 5 hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. The 5-HT5A Receptor is a member of the Serotonin Receptor subfamily.Synonyms: 5-HT-5, 5-HT-5A, 5-HT5A, 5-hydroxytryptamine receptor 5A

Gene ID: 3361

NCBI Accession: NP_076917

UniProt: P47898

Pathways: JAK-STAT Signaling