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Antibodies
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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) antibody
Chemokine (C-C Motif) Receptor 4 (CCR4) antibody
| Antigen |
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| Synonyms |
CKR4, K5-5, CD194, CMKBR4, ChemR13, CC-CKR-4, MGC88293, HGCN:14099 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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| Catalog no. |
ABIN302479 |
| Quantity |
50 µg (1.0 mg/ml) (Variants) |
| Price |
390.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CMKBR4, K5-5
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Alternative name
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CD194 / CCR4
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Swiss-Prot
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P51679
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Immunogen
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Synthetic peptide - KLH conjugated, 2nd extracellular domain of humanRemarks: Mouse Identity: 83 %Mouse Similarity: 94 %Rat Identity: 83 %Rat Similarity: 94 %
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Cross-Reactivity
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Human
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Description
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CCR4, a Chemokine Receptor, mediates inflammatory responses and HIV-1 infections. Itbinds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulatedchemokine) and MDC (macrophage-derived chemokine).
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Specificity
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This antibody detects C-C Chemokine Receptor 4 (CCR4) at 2nd extracellular domain. Species: Human. Others not tested.
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Application Notes
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Immunohistochemistry on paraffin sections (10 ug/ml). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1.0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline containing 0.09% sodium azide
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Storage
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Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Chemokines, Receptors
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-C Motif) Receptor 4 (CCR4)", type "Antibodies"
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Hosts
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Rabbit (7), Mouse (1)
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Reactivities
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Human (7), Mouse (Murine) (4), Rat (Rattus) (3), Dog (Canine) (2), Cow (Bovine) (1), Monkey (1)
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Applications
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Western Blotting (WB) (5), Enzyme Immunoassay (EIA) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Flow Cytometry (FACS) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1)
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