Prostaglandin E Synthase antibody (N-Term)

Catalog No. ABIN302586

The Rabbit Polyclonal anti-Prostaglandin E Synthase antibody (ABIN302586) specifically detects Prostaglandin E Synthase in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Prostaglandin E Synthase antibody (N-Term) (ABIN302586)

Target: Prostaglandin E Synthase (PTGES)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostaglandin E Synthase antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Prostaglandin E Synthase Antibody

Binding Specificity: N-Term

Specificity: This antibody detects Prostaglandin E Synthase (PTGES) near N-terminus.

Purification: Immunoaffinity chromatography

Immunogen: PTGES antibody was raised against synthetic peptide from near N-terminus of human PTGES.

Application Details

Application Notes: Immunohistochemistry on paraffin sections (10 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Target Details for Prostaglandin E Synthase

Target: Prostaglandin E Synthase (PTGES)

Alternative Name: PTGES

Background: PGES-1 is a membrane associated protein involved in eicosanoid and glutathione metabolism as part of the arachidonic acid signaling pathway. The expression of this protein is induced by the proinflammatory cytokine IL-1B and its' activity is glutathione dependent. PGES is also expressed at high levels in P53 expressing cells.Synonyms: MGST1-L1, MGST1L1, MPGES-1, MPGES1, PGES, PIG12, Prostaglandin E synthase, p53-induced gene 12 protein

Gene ID: 9536

NCBI Accession: NP_004869

UniProt: O14684