RAP1 antibody (AA 2406-2419)

Catalog No. ABIN302914

This Rabbit Polyclonal antibody specifically detects RAP1 in WB, IF, IHC (p) and EIA. It exhibits reactivity toward Human, Mouse, Rat, Dog and Monkey.

Quick Overview for RAP1 antibody (AA 2406-2419) (ABIN302914)

Target: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-RAP1 Antibody

Binding Specificity: AA 2406-2419

Specificity: This antibody recognizes amino acids 2406-2419 of Rif1.

Cross-Reactivity (Details): Species reactivity (expected):Chimpanzee, Canine, Human, RatSpecies reactivity (tested):Mouse

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide corresponding to amino acids 2406-2419 of Mouse Rif1

Application Details

Application Notes: Immunofluorescence. Immunohistochemistry on paraffin sections: 5 μg/mL. ELISA: 1: 5000 - 1: 40000. Western Blot: 1: 500 - 1: 3000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.

Target Details for RAP1

Target: RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))

Alternative Name: TERF2IP / RAP1

Background: Rif1 (also known as telomere-associated protein RIF1 and Rap1-interacting factor 1) is a mouse ortholog of the yeast Rif1 family of telomere-associated proteins identified on the basis of its high expression in primordial germ cells and embryo-derived pluripotent stem cell lines. Mouse Rif1 is a protein involved in negative regulation of telomere length. It is also localized to ATM dependent DNA damage foci and may act at the chromatin level to allow access to some factors.Synonyms: PP8000, TRF2-interacting telomeric protein Rap1, Telomeric repeat-binding factor 2-interacting protein 1

Gene ID: 54386

NCBI Accession: NP_061848

UniProt: Q9NYB0

Pathways: Cell Division Cycle, Telomere Maintenance