Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10) (C-Term) antibody

Antigen: Transmembrane Emp24-Like Trafficking Protein 10 (Yeast) (TMED10)

Synonyms: TMP21, S31I125, Tmp-21-I, S31III125, P24(DELTA)

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN303302

Additional Information

Characteristics: Synonyms: S31I125, Transmembrane emp24 domain-containing protein 10, 21 kDatransmembrane-trafficking protein, Transmembrane protein Tmp21

Alternative name: TMED10 / TMP21

Swiss-Prot: P49755

Immunogen: Synthetic Peptide corresponding to 19 amino acid peptide from near the carboxy terminusof human TMP21.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Description: TMP21 is a integral membrane protein that is localized in microsomal membranes,zymogen granule membrane and the plasma membrane. It is ubiquitously expressed andis involved in vesicular targeting and protein transport. Recent studies have shown thatTMP21 is a component of presenillin complexes and differentially regulatesgamma-secretase cleavage of the amyloid precursor protein, without affectingepsilon-secretase activity.

Specificity: Species: Human, Mouse and Rat. Others not tested.

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections (3 ug/ml). Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Purification: Purified

Buffer: Phosphate Buffered Saline PBS containing 0.02% Sodium Azide aspreservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only