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S1PR1 antibody (AA 25-40)
S1PR1
Reactivity: Human
IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-S1PR1 Antibody
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Target
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S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Binding Specificity
All epitopes for S1PR1 antibodies
AA 25-40
Reactivity
All reactivities for S1PR1 antibodies
Human
Host
All hosts for S1PR1 antibodies
Rabbit
Clonality
All clonalities for S1PR1 antibodies
Polyclonal
Conjugate
All conjugates for S1PR1 antibodies
This S1PR1 antibody is un-conjugated
Application
All applications for S1PR1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognises EDG1.
Purification
Protein G Chromatography.
Immunogen
Synthetic peptide - KLH conjugated corresponding to Peptide corresponding to amino acids 25-40 of human Edg1.
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Discover our top product S1PR1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Immunohistochemistry on Paraffin Sections (10 μg/mL). ELISA (1/0-1/1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate Buffered Saline PBS containing 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid cycles of freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
Target Details for S1PR1
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Target
S1PR1
(Sphingosine-1-Phosphate Receptor 1 (S1PR1))
Alternative Name
EDG-1 / S1PR1 (S1PR1 Products )
Synonyms
CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
Background
EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG-1 leads to increased cell-cell aggregation and overexpression of cadherins.Synonyms: CHEDG1, D1S3362, ECGF1, EDG1, Endothelial differentiation G-protein coupled receptor 1, FLJ58121, S1P receptor 1, S1PR1, Sphingosine 1-phosphate receptor 1
Gene ID
1901
NCBI Accession
NP_001391
UniProt
P21453
Pathways
Signaling Events mediated by VEGFR1 and VEGFR2
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