ADAR1 (Adenosine Deaminase Acting On RNA 1) (AA 1116-1176) antibody

Catalog No. ABIN306686

The Sheep Polyclonal anti-ADAR1 (Adenosine Deaminase Acting On RNA 1) antibody is suitable to detect ADAR1 (Adenosine Deaminase Acting On RNA 1) in samples from Rat. It has been validated for WB.

Quick Overview for ADAR1 (Adenosine Deaminase Acting On RNA 1) (AA 1116-1176) antibody (ABIN306686)

Target: ADAR1 (Adenosine Deaminase Acting On RNA 1)

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: AA 1116-1176

Cross-Reactivity: Rat

Characteristics: DRADA, double strandard RNA specific adenosine deaminase 1, ADAR1,Double stranded RNA specific adenosine deaminase 1 (ADAR1 or DRADA) is an enzyme involved in the editing of mammalian messenger RNAs by the site specific conversion of adenosine to inosine. ADAR 1 is thought to play a role in the editing of transcripts encoding non-NMDA glutamate receptor subunits, the 2C subtype of serotonin receptor, as well as hepatitis delta virus antigen.

Purification: Antigen Immunoaffiinity Purification

Immunogen: Sheep were immunized with a GST fusion protein containing amino acid 1116-1176 of the rat DRADA coding sequence. The fusion protein was constructed in the pGEX-KG vector by inserting a fragment corresponding to nucleotides +3346 through +3525 of DRADA at the XbaI and XhoI sites in the vector.

Isotype: IgG

Application Details

Application Notes: Immunoblotting - recommended dilution of 1:1000.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: ADAR1 (Adenosine Deaminase Acting On RNA 1)