LPAR3 antibody (C-Term)

Catalog No. ABIN306802

This Rabbit Polyclonal antibody specifically detects LPAR3 in WB. It exhibits reactivity toward Human.

Quick Overview for LPAR3 antibody (C-Term) (ABIN306802)

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LPAR3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti Human Lysophosphatidic Acid Receptor 3 CT (EDG-7)

Cross-Reactivity: Human

Characteristics: Endothelial Cell Differentiation Gene-7 (EDG-7) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-7 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.

Purification: Ammonium Sulfate Precipitation

Immunogen: Antibody raised against a unique synthetic peptide derived from the C-terminal of the human EDG7 protein.

Isotype: IgG

Application Details

Application Notes: Detects recombinant EDG-7 receptors by Western blot. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for LPAR3

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Alternative Name: Lysophosphatidic Acid Receptor 3 CT (EDG-7)

Background: Endothelial cell differentiation gene 7 C-terminal, Lysophosphatidic Acid Receptor-4 (LPA3)

UniProt: Q9UBY5

Pathways: Regulation of Cell Size