Kein 7 7 antibody
The Mouse Monoclonal anti-Kein 7 7 antibody (Clone C46) (ABIN306825) specifically detects Kein 7 7 in IHC (fro) and WB.
The antibody is reactive with Human samples.
Catalog No. ABIN306825
$368.50
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
Quick Overview for Kein 7 7 antibody (ABIN306825)
Target
Kein 7 7
Reactivity
Human
Host
Mouse
Clonality
Monoclonal
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
Clone
C46
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Purpose
- Mouse anti Human Keratin 7 (7, 17)
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Cross-Reactivity
- Human
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Characteristics
- Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie., skin) and non-keratinizing cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. Atleast 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
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Purification
- Protein A/G Chromatography
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Immunogen
- Hybridoma produced by the fusion of splenocytes from mice immunized with cytoskeleton preparation from HeLa cells and mouse myeloma cells.
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Isotype
- IgG1
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Application Notes
- Detects keratin 7 and 17 by Western blot. Detects a 54 kDa band, corresponding to keratin 7, and a 46 kDa band, corresponding to keratin 17. Reacts only with keratin 7 in formalin-fixed paraffin-embedded sections. Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Kein 7 7
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Alternative Name
- Kein 7 (7
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UniProt
- P08729
Target
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