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Voltage-gated Calcium Channel Subunit alpha-2/delta-1 (CACNA2D1) antibody

Antigen

Voltage-gated Calcium Channel Subunit alpha-2/delta-1 (CACNA2D1)

Synonyms CCHLA2, Cacna2, DHSCCA
Clonality Polyclonal
Host

Rabbit

Reactivity

Human, Rat (Rattus)

Application
Western Blotting (WB)
Catalog no. ABIN306883
Quantity 100 ug  (1 mg/ml)
Price 210.00 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information

Alternative name L-type calcium channel alpha2/delta subunit
Swiss-Prot Q8VHS9
Isotype IgG  (Matching secondary antibodies)
Description The calcium channel alpha2/delta subunit is a glycosylated structural subunit consisting of the alpha2 subunit and the delta peptide. There is distinctive alpha2 subunit expression in rat spinal cord and dorsal root ganglia (DRG) There are two forms of the alpha2 subunit in DRG that are different from the alpha2 subunit in other tissues examined, at least at the glycosylation level. Thus, post-translational modification may be important in tissue specific and functional expression of the alpha2/delta subunit (2). alpha2/delta and beta1b interact with alpha1G to increase trafficking of, or stabilize, functional alpha1G channels expressed at the plasma membrane.(3)

Application Details

Application Notes This antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Rat brain lysate.
Concentration 1 mg/ml
Storage Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Restrictions For Research Use only