Ceramide Kinase (rProtein-Full Length) antibody

Catalog No. ABIN306953

The Rabbit Polyclonal anti-Ceramide Kinase (rProtein-Full Length) antibody is suitable to detect Ceramide Kinase (rProtein-Full Length) in samples from Human. It has been validated for ELISA and WB.

Quick Overview for Ceramide Kinase (rProtein-Full Length) antibody (ABIN306953)

Target: Ceramide Kinase (rProtein-Full Length)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Western Blotting (WB)

Product Details

Purpose: Rabbit anti Human Ceramide Kinase (rProtein-Full Length)

Cross-Reactivity: Human

Characteristics: Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondria-mediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.

Application Details

Application Notes: Antibody can be used for Western blotting (1-10 μg/mL). Can also be used for ELISA. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: Ceramide Kinase (rProtein-Full Length)

Background: Acylsphingosine kinase, hCERK, Lipid kinase 4, LK4

UniProt: Q8TCT0