DEGS1 antibody

Catalog No. ABIN307135

This Rabbit Polyclonal antibody specifically detects DEGS1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DEGS1 antibody (ABIN307135)

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEGS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DEGS1 Antibody

Purpose: Rabbit anti Human Degenerative Spermatocyte Homolog 1 (DEGS1)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the human DEGS1 protein

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (1-5 μg/mL starting dilution). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for DEGS1

Target: DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Alternative Name: Degenerative Spermatocyte Homolog 1 (DEGS1)

Background: Migration-inducing gene 15 protein, MLD, dihydroceramide desaturase, sphingolipid delta 4 desaturase, DES1, MGC5079, DEGS

UniProt: O15121