NSMAF antibody

Catalog No. ABIN307148

The Rabbit Polyclonal anti-NSMAF antibody is suitable to detect NSMAF in samples from Human. It has been validated for WB.

Quick Overview for NSMAF antibody (ABIN307148)

Target: NSMAF (Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSMAF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSMAF Antibody

Purpose: Rabbit anti Human FAN, N-SMase Activation Associated Factor

Cross-Reactivity: Human

Characteristics: Novel adaptor protein which mediates the activation of sphingomyelinase by receptors such as tumor necrosis factor receptor type 1 and CD40 and subsequent apoptosis in cardiomyocytes. Inhibition of this factor may provide a novel intervention point for reducing ischemia/reperfusion injury.

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from human NSMAF protein.

Application Details

Application Notes: Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for NSMAF

Target: NSMAF (Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF))

Alternative Name: N-SMase Activation Associated Factor

Background: FAN (Factor associated with neutral sphingomyelinase activation) SMAF, Neutral sphingomyelinase (N-SMase) activation associated factor

UniProt: Q8IW26