SLC16A7 antibody
Quick Overview for SLC16A7 antibody (ABIN307153)
Target
See all SLC16A7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit anti Human Monocarboxylate Transport 2
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Cross-Reactivity
- Human
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Characteristics
- Functions as a proton-linked monocarboxylate transporter and catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a very high affinity pyruvate transporter. MCT2 is a cell membrane, Multi-pass membrane protein with high expression in testis, moderate to low expression in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes. The normal expression of MCT2 is restricted to low levels of expression in normal tissues, but is widely expressed in cancer cells.
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Purification
- Ammonium Sulfate Precipitation
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Immunogen
- Synthetic peptide derived from human MCT2 protein
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Application Notes
- Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SLC16A7 (Solute Carrier Family 16, Member 7 (Monocarboxylic Acid Transporter 2) (SLC16A7))
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Alternative Name
- Monocarboxylate Transport 2
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Background
- MCT2, Solute carrier family 16 member 7, SLC16A7
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UniProt
- O60669
Target
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