RBPJL antibody (N-Term)

Catalog No. ABIN309728

The Rabbit Polyclonal anti-RBPJL antibody is suitable to detect RBPJL in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig and Horse. It has been validated for WB.

Quick Overview for RBPJL antibody (N-Term) (ABIN309728)

Target: RBPJL (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBPJL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBPJL Antibody

Binding Specificity: N-Term

Purpose: RBPJL Antibody - N-terminal region

Sequence: AHQAGETGPT VCGYMGLDSA SGSATETQKL NFEQQPDSRE FGCAKTLYIS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RBPJL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBPJL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110165

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBPJL

Target: RBPJL (Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL))

Alternative Name: RBPJL

Background:

Background Information: In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPSUHL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

Gene Name: Recombination signal binding protein for immunoglobulin kappa J region-like

Alternative Symbols: RBPL, SUHL, RBPSUHL

Protein Name: Recombining binding protein suppressor of hairless-like protein

Molecular Weight: 57kDa

Gene ID: 11317

NCBI Accession: NP_055091

UniProt: Q5QPV0