CXXC1 antibody (C-Term)

Catalog No. ABIN309931

This Rabbit Polyclonal antibody specifically detects CXXC1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Goat, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CXXC1 antibody (C-Term) (ABIN309931)

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CXXC1 Antibody

Binding Specificity: C-Term

Sequence: RVWYKLDELF EQERNVRTAM TNRAGLLALM LHQTIQHDPL TTDLRSSADR

Predicted Reactivity: Cow: 86%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CXXC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CXXC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 656 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CXXC1

Target: CXXC1 (CXXC Finger Protein 1 (CXXC1))

Alternative Name: CXXC1

Background: Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression.Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001).[supplied by OMIM].
Alias Symbols: 2410002I16Rik, 5830420C16Rik, CGBP, HsT2645, PCCX1, PHF18, hCGBP, CFP1, SPP1, ZCGPC1
Protein Interaction Partner: RBBP5, MEOX2, WDR5, SETD1A, ASH2L, TAX1BP1, WDR82, UBC, RNF2, HSP90AA1, SETD1B, TBP, MYC, SUMO2, PPP1CA, tat, NR5A1, SMURF1, HIST2H3C, HIST2H4A, MEN1, KIFC1, DNMT1, WDR82P1, WDR77, KMT2D, KMT2A,
Protein Size: 656

Molecular Weight: 76 kDa

Gene ID: 30827

NCBI Accession: NM_014593, NP_055408

UniProt: Q9P0U4

Pathways: ER-Nucleus Signaling